LYCOS RETRIEVER 
Erythromycin: Patients
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Treponema pallidum: Erythromycin is an alternate choice of treatment for primary syphilis in patients allergic to the penicillins. In treatment of primary syphilis, spinal fluid examinations should be done before treatment and as part of follow-up after therapy.
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Erythromycin is similar in use to penicillin and is widely used for patients who are allergic to penicillin. Penicillin has advantages over erythromycin in that it kills bacteria, while erythromycin only stops bacterial growth and relies on the body's immune system to kill bacteria. Also, erythromycin is more likely to cause stomach upset than is penicillin. Sometimes erythromycin may be used to treat a microorganism that is resistant to penicillin.
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- Erythromycin is contraindicated in patients hypersensitive to it. In humans, the estolate form has been associated rarely with the development of cholestatic hepatitis. This effect has not apparently been reported in veterinary species, but the estolate should probably be avoided in patients with preexisting liver dysfunction.
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