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Endometriosis: Theories
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Web Toolkit The cause of endometriosis is not known. There are ... several theories. The leading theory, at present, links endometriosis to a problem with the immune system. A weakness in the immune system may allow endometrial tissue to take root and grow outside the uterus in women with endometriosis.
The autoimmune theory proposes that women with certain genetic factors develop endometriosis when they’re exposed to certain environmental triggers. This theory is supported by the fact that endometriosis tends to run in families. In addition, certain environmental toxins such as PCBs, DDT, and Dioxin and other environmental endocrine disruptors are all associated with endometriosis.
There is strong evidence to suggest that endometriosis may be genetic. Women who have a family history of the problem are more likely to have it, as are their daughters. Other experts believe that endometriosis is actually part of a larger immunological disorder. This is based on the fact that women with endo have a higher likelihood of developing other problems including lupus, allergies, and an under active thyroiditis (hypothyroidism) or over active thyroiditis (hyperthyroidism). One of the more convincing theories, and a possible explanation as to why endo is occurring more frequently and at a younger age, is that endometriosis is related to environmental toxins, in particular dioxin.
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