LYCOS RETRIEVER
Ebola: Ebola Reston
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Ebola Hemorrhagic Fever is an often fatal disease caused by the Ebola virus and has appeared in outbursts since its initial recognition. The Ebola virus is classified under the Filovirus family. There are ... four types of the Ebola virus: Ebola-Zaire, Ebola-Sudan, Ebola-Ivory Coast(Tai), and Ebola-Reston. Filoviruses are classified as biosafety level 4 agents because of their extreme pathogenicity and the lack of a vaccine or effective antiviral drug (www.cdc.gov). Their natural history and reservoirs remain undefined and their pathogenesis is poorly understood.
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Ebola viruses are a group of exotic viral agents that cause a severe hemorrhagic fever disease in humans and other primates. The four known subtypes or species of Ebola viruses are Zaire, Sudan, Reston, and Côte d'Ivoire (Ivory Coast), named for the geographic locations where these viruses were first determined to cause outbreaks of disease. Ebola viruses are very closely related to, but distinct from, Marburg viruses. Collectively, these pathogenic agents make up a family of viruses known as the Filoviridae.
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The exact origin, locations, and natural habitat (known as the "natural reservoir") of Ebola virus remain unknown. However, on the basis of available evidence and the nature of similar viruses, researchers believe that the virus is zoonotic (animal-borne) and is normally maintained in an animal host that is native to the African continent. A similar host is probably associated with Ebola-Reston which was isolated from infected cynomolgous monkeys that were imported to the United States and Italy from the Philippines. The virus is not known to be native to other continents, such as North America.
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Ebola Reston had a kill ratio of 90%, like the other strains, but appeared to burn through the monkey stock in a matter of days rather than weeks. The incredibly fast motion of Ebola Reston makes it the most lethal strain so far. That four humans contracted it makes it cross-species capable, which scares the living hell out of most medical facilities, but the capacity to jump species is underscored by the apparent fact that Ebola Reston's symptoms in the human species are atypical of most other Ebola strains.
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Confirmed cases of Ebola HF have been reported in the Democratic Republic of the Congo, Gabon, Sudan, the Ivory Coast, Uganda, and the Republic of the Congo. An individual with serologic evidence of infection but showing no apparent illness has been reported in Liberia, and a laboratory worker in England became ill as a result of an accidental needle-stick. No case of the disease in humans has ever been reported in the United States. Ebola-Reston virus caused severe illness and death in monkeys imported to research facilities in the United States and Italy from the Philippines; during these outbreaks, several research workers became infected with the virus, but did not become ill.
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In 1989, Ebola-Reston was discovered in an outbreak in a primate quarantine facility in the United States, but did not cause illness in infected humans. Ivory Coast was discovered in an outbreak in 1994.
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