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Disease: Graves' Disease
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Graves' Disease is a type of autoimmune disease that causes over-activity of the thyroid gland, causing hyperthyroidism. This over-activity is ... sometimes called "toxic diffuse goiter." The thyroid gland helps set the rate of metabolism, which is the rate at which the body uses energy. When the thyroid is too active, it makes more thyroid hormones than the body needs. High levels of thyroid hormones can cause side effects such as weight loss, rapid heart rate and nervousness. This is an uncommon disease that affects 2 percent of all women at some time in their lives. Graves’ Disease also tends to affect women between the ages of 20 and 40, although it occurs in infants, children, and the elderly.
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Studies have shown that the TRAb test has the highest diagnostic power to differentiate Graves' disease from toxic nodular goiters. KreLo GmbH focuses on research and development of diagnostic kits for application in human medicine. It was co-founded by Werner Kress and Prof. Ulrich Loos, formerly professor at the Department of Medicine at Ulm University (Ulm, Germany). Prof. Loos is the CEO of KreLo GmbH.
[One] test, called a Thyroid Stimulating Immunogobulin (TSI), might be used if your doctor is unsure about whether you have the disease, or for patients who have a Graves’ disease eye disorder but normal thyroid function. It can ... be used to check a Graves’ disease patient’s response to treatment. TSI is also measured in pregnant women who have hyperthyroidism to diagnose Graves' disease and to assess the risk to the baby.
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"The new TRAb assay has enormous potential to help diagnose, monitor and predict the course of Graves' disease," said Joe Bernardo, senior vice president, Central Lab Testing, Siemens Medical Solutions Diagnostics. "Siemens continues to focus on new biomarker development opportunities, continually expanding our already comprehensive immunoassay menu and providing the diagnostic tools necessary to diagnose and treat millions of thyroid disease patients."
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