LYCOS RETRIEVER 
Disease: Disease Vaccine
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PHILADELPHIA, Jan. 12 /PRNewswire/ -- LYMErix(TM) [Lyme Disease Vaccine (Recombinant OspA)], the world's first vaccine to prevent Lyme disease, is now available. Manufactured by SmithKline Beecham Biologicals (NYSE: SBH), LYMErix(TM) was proven safe and effective in the prevention of both definite Lyme disease (characteristic symptoms with serologic and culture diagnosis) and asymptomatic infection (no symptoms, but serologic diagnosis). LYMErix(TM) received approval from the U.S. Food and Drug Administration in December, 1998.
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The company’s lead products are based on ImmunoStimulatory Sequences (ISS), short DNA sequences that enhance the ability of the immune system to fight disease and prevent inflammation. The company’s two most advanced products are AIC, which has provided positive results in recently completed phase II clinical trials for the treatment of ragweed allergy, and a next-generation hepatitis B vaccine that may offer single-dose protection. Dynavax is ... developing an oral TNF-alpha synthesis inhibitor initially for the treatment of rheumatoid arthritis. The company has collaborations with Aventis-Pasteur, Triangle Pharmaceuticals and Stallergenes.
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Lyme disease is caused by a bacteria which is transmitted via the bite of ticks that live on deer or white-footed mice. In rare cases, and if untreated, Lyme disease can lead to arthritis and neurological problems. This is the first year that there is a safe, effective, FDA-approved vaccine against Lyme disease available prior to tick season. The first Lyme disease vaccine, known as LYMErix, was approved in December 1998 by the FDA. A second vaccine, ImuLyme, is pending FDA approval.
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An estimated 1,400 to 2,800 cases of meningococcal disease occur annually in the United States. Meningococcal disease can have severe complications and can be life threatening. About 76 percent of cases of meningococcal disease among 11-19 year olds are vaccine-preventable.
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Editor note: In February 2002 the maker of LYMErix (the Lyme disease vaccine) announced they would stop producing the vaccine due to "insufficient consumer demand" The CDC reports, the protection provided by this vaccine does diminish over time. Therefore, if you received this Lyme disease vaccine before 2002, you are probably no longer protected against Lyme disease.
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