LYCOS RETRIEVER 
Dermatitis: Diseases
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Even though exfoliative dermatitis is a complex disorder involving many factors, the underlying disease is usually the key determinant of the course and prognosis. Drug-induced exfoliative dermatitis is usually short-lived once the inciting medication is withdrawn and appropriate therapy is administered. Patients with underlying skin disorders may respond much more slowly to therapy, but clearing almost always occurs eventually. The clinical course of patients with malignancies depends on the type of malignancy and the response to appropriate therapy. Patients who have exfoliative dermatitis of unknown cause tend to have an unpredictable course, usually replete with multiple remissions and exacerbations.4
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The terms eczema and dermatitis describe a reaction pattern of skin disorders with a variety of common characteristics. The acute disease typically is characterized by inflammation, redness, swelling, and itching, as well as some blistering and oozing. Skin biopsies show inflammatory cells and swelling.
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Although the term eczema is often used for atopic dermatitis, there are several other skin diseases that are eczemas as well. Eczema is a general term for all types of dermatitis. Dermatitis is a medical term meaning “inflammation of the skin.”
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Most cases of atopic dermatitis are too severe for self-care by parents/caregivers. "Proper, early and regular treatment by a dermatologist can bring relief and may reduce the severity and duration of the disease," says Dr. Kahn.
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The findings could shed light on atopic dermatitis patients' susceptibility to eczema vaccinatum, a widespread skin infection that can afflict those who receive the smallpox vaccination. They may have relevance for other diseases, as well. For instance, it is known that tuberculosis and leprosy patients, whose cells secrete the same immune system regulators as atopic dermatitis patients, are more likely to have disease that spreads widely in their bodies.
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Although scientists are working to develop safer vaccines, persons diagnosed with atopic dermatitis (or eczema) should not receive the current smallpox vaccine. According to the Centers for Disease Control and Prevention (CDC), a U.S. Government organization, persons who have ever been diagnosed with atopic dermatitis, even if the condition is mild or not presently active, are more likely to develop a serious complication if they are exposed to the virus from the smallpox vaccine.
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