LYCOS RETRIEVER 
Deafness: Genes
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Acquired deafness may or may not be genetic. For example, it may be a manifestation of a delayed-onset form of genetic deafness. Alternatively, acquired deafness may be due to damage to the ear from noise.
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Scientists have discovered that mice genetically engineered to lack a particular protein in the brain have profound deafness and seizures. The finding suggests a pathway, they say, for exploring the hereditary causes of deafness and epilepsy in humans.
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In the future, hearing screenings will likely look for this gene mutation as a possible cause for non-syndromic deafness, especially in African Americans. Non-syndromic deafness means that no other patient problems or symptoms are present that are known to cause deafness.
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The trait for deafness is tied to the genetics of coat colour, particularly in breeds with the merle or piebald gene. There is an increased risk of deafness with increasing amounts of white in the coat.
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![[icona.jpg]](http://retrieverimages.lycos.com/images/d/e/a/deafness/i/024.jpg)
Other connexin genes are ... involved in deafness. These are GJB1 (Cx32), which is also responsible for X-linked Charcot-Marie-Tooth disease type I; GJB3 (Cx31), involved in both deafness or a skin disease, erythrokeratodermia variabilis, depending on the location of the mutation; GJB6 (Cx30), which has been related to a dominant type of deafness in an Italian family and NEW GJA1 (Cx43), which has recently been shown to be involved in recessive deafness.
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