LYCOS RETRIEVER 
Cytotec: Misoprostol Acid
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Nursing mothers: It is unlikely that Cytotec is excreted in human milk since it is rapidly metabolized throughout the body. However, it is not known if the active metabolite (misoprostol acid) is excreted in human milk. Therefore, Cytotec should not be administered to nursing mothers because the potential excretion of misoprostol acid could cause significant diarrhea< in nursing infants.
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Cytotec protects the lining of your stomach by: stopping stomach acid secretions that usually build up at night. Cytotec reduces the volume of these stomach secretions; the amount of activity of stomach fluids, and ... increases the amount of bicarbonates secretions in your stomach.
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Cytotec® (Misoprostol) is a synthetic analogue of Prostaglandin E1 (PGE1). Like endogenous PGE1, Cytotec® exerts a protective effect on the gastrointestinal mucosa by increasing mucus and bicarbonate ion secretion and by increasing mucosal blood flow. In addition, Cytotec® inhibits acid secretion.
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Cytotec is rapidly absorbed following oral administration, with peak plasma levels of the active metabolite (misoprostol acid) occurring after about 30 minutes. The plasma elimination half-life of misoprostol acid is 20-40 minutes. No accumulation of misoprostol acid in plasma occurs after repeated dosing of 400 micrograms twice daily.
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In clinical trials, there was no evidence of interaction between Cytotec® and cardiac, gastrointestinal, pulmonary, or central nervous system drugs Decreased bioavailability of Misoprostol Acid was observed with high doses of antacid. However, low doses of antacids administered during ulcer healing trials had no effect on the efficacy of Cytotec®
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Misoprostol Acid