LYCOS RETRIEVER 
Cystitis: Interstitial
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Interstitial cystitis can be a very painful condition as it is a chronic inflammation of the bladder. People who suffer from interstitial cystitis lack the protective lining that protects the bladder from the toxins that occur naturally in the urine. This lining consists of proteins called gylcoaminooglycan. Once this layer has been broken down by interstitial cystitis, toxins are then free to irritate and inflame the wall of the bladder. Once enflamed, the bladder becomes tender and its ability to store urine is diminished significantly.
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There is no single correct way to make the diagnosis of interstitial cystitis. Many specialists begin the patient evaluation with an extensive history to understand which organ systems are involved, followed by a physical examination directed towards the involved organ systems. Abdominal, genital, and rectal examinations may help localize specific areas of pathology. Basic urinary laboratory tests ... are performed.
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IC is frequently misdiagnosed as an acute urinary tract infection (cystitis), a disorder which can be successfully treated with antibiotics. A cystoscopy with hydrodistention under general anesthesia is required to make a diagnosis of interstitial cystitis. The bladder is distended to check for pinpoint hemorrhages on the bladder wall that are the hallmark of IC.
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Research has observed that both the acidity of decaffeinated and regular coffee intake increases pain in cystitis sufferers. For people who have interstitial cystitis, drinking just one cup of coffee can trigger hours of pain and agonizing trips to the bathroom. You can decrease your pain by avoiding acidic drinks like coffee.
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Some, but not all, investigators recommend cystoscopic examination with hydrodistention under anesthesia for the evaluation of interstitial cystitis. As noted by Denton and colleagues, a significant number of patients thought by history and physical examination to have interstitial cystitis do not have any significant abnormal findings on cystoscopy. Cystoscopic evaluation of interstitial cystitis includes the following:
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The incidence of interstitial cystitis is much greater in females than in males. As with urethral syndrome (see above), many other more common urologic problems are diagnosed incorrectly before the proper diagnosis is made. Interstitial cystitis must be diagnosed with the use of the cystoscope, an instrument which can directly visualize the interior of the bladder.
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