LYCOS RETRIEVER 
Cyclobenzaprine
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Cyclobenzaprine is available with a prescription under the brand name Flexeril. Other brand or generic formulations may ... be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.
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Cyclobenzaprine is extensively metabolized, and is excreted primarily as glucuronides via the kidney. Cytochromes P-450 3A4, 1A2, and, to a lesser extent, 2D6, mediate N-demethylation, one of the oxidative pathways for cyclobenzaprine. Cyclobenzaprine is eliminated quite slowly, with an effective half-life of 18 hours (range 8-37 hours; n=18); plasma clearance is 0.7 L/min.
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Cyclobenzaprine is regulated in the U.S. for prescription use only. Cyclobenzaprine does not fall within most governmental guidelines as a controlled substance... possession without a valid / current prescription may be illegal depending upon various state and local laws.
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Cyclobenzaprine is well absorbed after oral administration, but there is a large intersubject variation in plasma levels. Cyclobenzaprine is eliminated quite slowly with a half-life as long as one to three days. It is highly bound to plasma proteins, is extensively metabolized primarily to glucuronide-like conjugates, and is excreted primarily via the kidneys.
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Cyclobenzaprine