LYCOS RETRIEVER 
Cordarone: Drugs
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Cordarone and one of its major metabolites, desethylamiodarone (DEA), are excreted in human milk, suggesting that breast-feeding could expose the nursing infant to a significant dose of the drug. Nursing offspring of lactating rats administered Cordarone have been shown to be less viable and have reduced body-weight gains. Therefore, when Cordarone therapy is indicated, the mother should be advised to discontinue nursing.
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Cordarone has recently been linked to Toxic Epidermal Necrolysis (TEN). Toxic Epidermal Necrolysis (TEN) is a rare condition that causes large portions of the epidermis, the skin's outermost layer, to disengage from the layers of skin below. The main cause of Toxic Epidermal Necrolysis (TEN) is from a severe drug reaction.
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Cordarone should be taken in or on a regular basis. If you are following a treatment with Cordarone, try not to miss any of your doses. If you happen to miss one take it as soon as possible and continue with your regular schedule. You should not take in a double dose of this drug unless you are instructed by your physician to do so.
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Since antiarrhythmic drugs may be ineffective or may be arrhythmogenic in patients with hypokalemia, any potassium or magnesium deficiency should be corrected before instituting and during Cordarone therapy. Use caution when coadministering Cordarone with drugs which may induce hypokalemia and/or hypomagnesemia.
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Drugs other than those listed here may ... interact with Cordarone. Talk to your prescriber or health care professional about other medicines that may increase the effect of Cordarone before taking any prescription or over-the-counter medicines.
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