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Clotrimazole
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Clotrimazole is a broad-spectrum, antifungal agent used for the treatment of superficial infections caused by species of pathogenic dermatophytes, yeasts, and Malassezia furfur. The mechanism of action involves inhibition of the synthesis of ergosterol, a major sterol in the fungal cell membrane. This leads to instability of the cell membrane and eventual death of the fungus.
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Canesten Clotrimazole kills the fungi that cause fungal infections (such as athlete’s foot, jock itch and all other fungal infections). It is a broad spectrum which means it treats a broad range of fungal types. This means you don't have to worry about what fungus type you are suffering from. Canesten Clotrimazole is non-greasy, non-staining and even odourless.
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Canesten Clotrimazole cream containing 14C-labelled clotrimazole was administered intravaginally to five women (four without gynaecological disorder and one with Candida vaginitis). A maximum serum level of 0.01 µg/mL was found between 10 and 30 hours after administration.
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Clotrimazole is not absorbed through your stomach. It will not treat fungal infections in any part of your body other than your mouth and throat. Talk to your doctor if you have another type of fungal infection such as athlete's foot, jock itch, ringworm, or a vaginal yeast infection.
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Clotrimazole cream should be applied to the affected area(s) of skin thinly two to three times daily and rubbed in gently. Treatment should be continued for at least one month for dermatophyte infections and at least two weeks for candidal infections. Ask your pharmacist for further advice on treating your particular infection.
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