LYCOS RETRIEVER 
Ciprofloxacin: Effects
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Ciprofloxacin may enhance the anti-blood-clotting effect of anticoagulant medicines such as warfarin. As this may increase the risk of bleeding, your blood clotting time (INR) should be monitored more frequently if you are taking ciprofloxacin with an anticoagulant.
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Ciprofloxacin is slightly less active when tested at acidic pH. The inoculum size has little effect when tested In Vitro. The minimum bactericidal concentration (MBC) generally does not exceed the minimum inhibitory concentration (MIC) by more than a factor of 2. Resistance to ciprofloxacin In Vitro develops slowly (multiple-step mutation).
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The antiacid medicaments (against increased stomach acidity) containing aluminum and magnesium decrease the effect of the Ciprofloxacin because they decrease its resorption by the gatro-intestinal tract. They have to be taken with an interval of 4 hours before or after the acceptance of Ciprofloxacin.
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