LYCOS RETRIEVER 
Chlorpheniramine
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Chlorpheniramine tablets and sustained-release tablets should be stored in tight containers. The sustained-release capsules should be stored in well-closed containers. The oral solution should be stored in light-resistant containers; avoid freezing. All chlorpheniramine products should be stored at room temperature (15-30°C).
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Hydrocodone-Chlorpheniramine should be stored at a temperature between 15 and 30 degrees Celsius (59 and 86 degrees Fahrenheit). It should be stored in a dry place and should not be frozen. The drug should be kept away from heat and direct sunlight.
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Chlorpheniramine is well distributed after IV injection, the highest distribution of the drug (in rabbits) occurs in the lungs, heart, kidneys, brain, small intestine and spleen. In humans, the apparent steady-state volume of distribution is 2.5 - 3.2 L/kg and it is about 70% bound to plasma proteins. It is unknown if chlorpheniramine is excreted into the milk.
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Chlorpheniramine competes with histamine for H1-receptor sites on effector cells in the gastrointestinal tract, blood vessels, and respiratory tract. Dexchlorpheniramine is the predominant active isomer of chlorpheniramine and is approximately twice as active as the racemic compound.
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Chlorpheniramine-hydrocodone can cause constipation. Make sure to take a laxative and/or a stool softener. Try to have a bowel movement at least every 2—3 days. If you do not have a bowel movement for 3 days or more call your prescriber or health care professional. They may recommend using an enema or suppository to help you move your bowels.
Chlorpheniramine may cause dry eyes and blurred vision. If you wear contact lenses you may feel some discomfort. Lubricating drops may help. See your ophthalmologist if the problem does not go away or is severe.
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Chlorpheniramine