LYCOS RETRIEVER 
Carbamazepine: Patients
built 622 days ago
Carbamazepine may antagonize the effects of non-depolarizing muscle relaxants (e.g. pancuronium). Their dosage may need to be raised, and patients should be monitored closely for more rapid recovery from neuromuscular blockade than expected.
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The used of Carbamazepine should be avoided in patients with a history of hepatic porphyria (e.g., acute intermittent porphyria, variegate porphyria, porphyria cutanea tarda). Acute attacks have been reported in such patients receiving Carbamazepine therapy. Carbamazepine administration has ... been demonstrated to increase porphyrin precursors in rodents, a presumed mechanism for the induction of acute attacks of porphyria.
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Carbamazepine is widely used for neuropathic pains of all types. This includes neuropathic pain on the face (trigeminal neuralgia), diabetes (diabetic neuralgia), and the shingles (post-herpetic neuralgia). As with all pain syndromes, the key is to increase the dose slowly until the pain is relieved or until the patient experiences some toxicity.
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Hypersensitivity reactions to Carbamazepine have been reported in patients who previously experienced this reaction to anticonvulsants including phenytoin and phenobarbital. A history of hypersensitivity reactions should be obtained for a patient and the immediate family members. If positive, caution should be used in prescribing Carbamazepine.
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Carbamazepine is used to treat patients with manic depressive disorder who fail to respond satisfactorily to other treatments such as lithium or who cannot tolerate those treatments. Carbamazepine may be used on its own or together with lithium. Carbamazepine is ... used to treat epilepsy and pain syndromes.
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