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Calcium
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Calcium Gluconate is the calcium salt of gluconic acid, an oxidation product of glucose, and contains 9.3% calcium, which is about one-third of the calcium in strength of calcium chloride USP. It has molecular formula C12H22CaO14 with a molecular weight of 430.38. Since it is soluble to the extent of only one proof in 30 parts of cold water, the 10% solution is supersaturated and is stabilized by the addition of calcium saccharate tetrahydrate 0.46% w/v (which supplies calcium 6.2%). Each mL contains 98 mg of calcium gluconate monohydrate, 4.6 mg of calcium saccharate tetrahydrate, and Water for Injection USP, q.s. Each mL provides 9.3 mg (0.465 milliequivalents) of calcium.
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Figure 1: Calcium Content of 8 fl oz of Milk Compared to Other Food Sources of Calcium Calcium, the most abundant mineral in the human body, has several important functions. More than 99% of total body calcium is stored in the bones and teeth where it functions to support their structure [1]. The remaining 1% is found throughout the body in blood, muscle, and the fluid between cells. Calcium is needed for muscle contraction, blood vessel contraction and expansion, the secretion of hormones and enzymes, and sending messages through the nervous system [2]. A constant level of calcium is maintained in body fluid and tissues so that these vital body processes function efficiently.
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Calcium lactate was significantly less stable with tartaric acid concentrations than calcium gluconate. Thus, a much lower tartaric acid concentration had to be achieved. This was accomplished by utilizing white grape concentrate and single strength clarified Niagara grape juice, which would yield 0.07 g/100 mls tartaric acid at 30% juice. Typical tartaric acid concentration for white concentrate is 0.097 g/100 mls while SS white grape juice has 0.4 g/100 mls. For a 15 gallon batch, a base was prepared consisting of 6.73 kg SS Niagara, 3.09 kg white grape concentrate, 3.50 kg 42F corn syrup, 2.74 kg sugar, 194.1 g citric acid, 22.5 g sodium citrate and 2 kg water. This base was then diluted with 41.16 kg of water and then 27.2 g of ascorbic acid and 612.3 g of calcium lactate were added and mixed thoroughly.
Calcium (Latin calx, meaning "limestone") was known as early as the first century when the Ancient Romans prepared lime as calcium oxide. It was not isolated until 1808 in England when Sir Humphry Davy electrolyzed a mixture of lime and mercuric oxide. Davy was trying to isolate calcium; when he heard that Berzelius and Pontin prepared calcium amalgam by electrolyzing lime in mercury, he tried it himself. He worked with electrolysis throughout his life and ... discovered/isolated sodium, potassium, magnesium, boron and barium.
Calcium is found in a wide variety of foods, but some foods are more rich in calcium than others. The food group with the most calcium is dairy - milk, yogurt and cheese. For instance, one cup of milk has about 300 mg of calcium. One ounce of cheese has about 200 mg. Other food sources rich in calcium include beans, almonds, oysters, and dark green leafy vegetables such as spinach and kale. The NIH recommends milk and other dairy products as a primary source of calcium. By eating a wide variety of foods with calcium, you can help make sure to get the calcium you need each day.
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