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Bactrim: Drugs
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Sulfamethoxazole, an ingredient in Bactrim, is one of a group of drugs called sulfonamides, which prevent the growth of bacteria in the body. Rare but sometimes fatal reactions have occurred with use of sulfonamides. These reactions include Stevens-Johnson syndrome (severe eruptions around the mouth, anus, or eyes), progressive disintegration of the outer layer of the skin, sudden and severe liver damage, a severe blood disorder (agranulocytosis), and a lack of red and white blood cells because of a bone marrow disorder.
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Bactrim is an antibacterial combination drug marketed by Hoffmann- La Roche Ltd. It is composed of trimethoprim and sulfamethoxazole, which together is coined as Co-trimoxazole. Bactrim is considered to be more effective than ordinary antibacterial drugs.
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Bactrim and other sulfa drugs are linked with Stevens Johnson Syndrome. Sulfamethoxazole, an ingredient in Bactrim, is one of a group of drugs called sulfonamides, which prevent the growth of bacteria in the body and which can trigger the life-threatening and devastating Stevens-Johnson syndrome. Wellcome, the maker of trimethoprim, and Hoffman-La Roche, the maker of sulphamethoxazole, combined their drugs in the 1960s to make the drug known as Bactrim. As cases of Bactrim-induced Stevens Johnson Syndrome are reported, it is becoming one of the top drugs associated with the potentially life-threatening disease. Hundreds of people are realizing that they are not alone in their experience with this dangerous drug.
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Bactrim is used to prevent and treat PCP and other infections. The risk of PCP is increased for transplant patients because of the drugs taken to suppress their immune systems, which reduce their bodies' ability to fight infection.
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Bactrim should be stored at room temperature away from heat, light, and moisture, which may cause the medication to break down. The liquid form of the bactrim drug should not be allowed to freeze.
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