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Augmentin: Patients
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As both the amoxycillin and clavulanic acid components of Augmentin are excreted by the kidneys, accumulation of both may occur in patients with renal insufficiency. In these cases monitoring of the serum levels and a reduction in the number of administrations of the suggested dosage may be required.
The side effects of Augmentin, which are primarily mild and self-limiting, include diarrhea and nausea. In adult patients treated for more severe infections during clinical trials, there was a significant reduction in the percentage of patients experiencing severe diarrhea or withdrawing from trials because of diarrhea: BID 1 percent versus TID 2.5 percent -- a reduction of 60 percent.
Source:
A moderate rise in Aspartate transaminase and/or Alanine transaminase has been noted in patients treated with Augmentin. The following adverse reactions have been reported for ampicillin class antibiotics and may occur with Augmentin.
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