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Augmentin: Amoxicillin
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Augmentin, a combination of Amoxicillin and Clavulanate, is one of a group of medicines called Penicillins and Beta-Lactamase inhibitors that are used to treat bacterial infections. Augmentin works by killing or preventing the growth of bacteria. Beta-Lactamase inhibitors are added to keep enzymes from destroying the penicillin before it can kill the bacteria.
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Generic Augmentin is an antibiotic used to treat or prevent the symptoms of Bacterial infections. Amoxicillin (Generic Augmentin) kills or stops the growth of bacteria that cause infection. Generic Augmentin treats many different kinds of infections, including those of the ears, kidney, respiratory tract, sinuses, and skin.
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Augmentin combines amoxicillin, an extended-spectrum antibiotic, with clavulanate, which inhibits an important mechanism of bacterial resistance. That mechanism is the production of beta-lactamases -- enzymes that destroy many antibiotics in both the penicillin and cephalosporin classes. By binding irreversibly to beta-lactamases, clavulanate protects amoxicillin from destruction.
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Augmentin contains two active ingredients that extends the antibiotic activity to a wider range of infections. The rationale behind this is due to the addition of clavulanic acid which has special activity against beta-lactamase producing bacteria. These infections can cause resistance against certain penicillin antibiotics including amoxicillin by itself.
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Augmentin 375 mg Tablets each contain 250 mg amoxicillin and 125 mg clavulanic acid. Both of these ingredients are antibiotics and together they are known as co-amoxiclav. The other ingredients in the tablets are: magnesium stearate (E572), sodium starch glycollate, colloidal silica, microcrystalline cellulose (E460), titanium dioxide (E171), hydroxypropyl methylcellulose (E464), polyethylene glycol and silicone oil. Each tablet contains 0.6 mg of sodium.
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