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Atenolol
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Atenolol is a cardioselective beta-blocker. Local anesthetic with vasoconstrictor can be safely used in patients medicated with atenolol. Nonselective beta-blockers (ie, propranolol, nadolol) enhance the pressor response to epinephrine, resulting in hypertension and bradycardia; this has not been reported for atenolol. Many nonsteroidal anti-inflammatory drugs, such as ibuprofen and indomethacin, can reduce the hypotensive effect of beta-blockers after 3 or more weeks of therapy with the NSAID. Short-term NSAID use (ie, 3 days) requires no special precautions in patients taking beta-blockers.
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Atenolol is in a group of drugs called beta-blockers. Beta-blockers affect the heart and circulation (blood flow through arteries and veins). Beta-blockers are used in the treatment of high blood pressure (hypertension). Atenolol is used to treat angina (chest pain) and hypertension (high blood pressure). It is ... used to treat or prevent heart attack. Atenolol may also be used for purposes other than those listed in this medication guide.
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Atenolol has a selective effect on B1-receptors and it can therefore be considered cardioselective. It does not have any intrinsic sympathomimetic effects. Atenolol reduces both maximal and submaximal heart rates and delays atrioventricular contraction. Atenolol can lead to a reduction in peripheral blood flow and to an increase of plasma triglycerides and total cholesterol as well as to reduced high density lipoprotein cholesterol values.
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In concomitant treatment with clonidin, Atenolol is withdrawn several days prior to clonidin interruption, in order to avoid the clonidin ?steal? syndrome. Atenolol intensifies the hypoglycemia, caused by sulphonylurea preparations, depressing the contraregulatory mechanisms; enhances the negative chronotropic and dromotropic effects of the centrally acting antihyprtensive drugs, as reserpin and methyldopa; accentuates antiarrhythmic capabilities of the calcium channel blocking agents (verapamil, diltiazem); potentiates action of the nondepolarizing neuromuscular blocking agents. Concomitant treatment with Atenolol and digitalis glycosides may lead to bradicardia and heart block, which requires an ECG-monitoring. Cimmetidin elevates the plasma level of the Atenolol and increases its effects. Concomitant application of NSAID may reduce the antihypertensive effect of Atenolol, due to suppression of the renal synthesis of prostaglandines as well as fluid and sodium ions retention.
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Answer: Atenolol belongs to a class of drugs called beta-blockers. These drugs block the beta receptors in the body. As a consequence, they are used in treating high blood pressure, hypertension, anxiety disorders, rapid heart beat syndromes and a host of other problems. The most common side effects of the beta-blockers are slow heart rates, fatigue, and occasional dyspnea. Hair loss is ... seen in about 1-5% of patients.
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Atenolol (trade name Tenormin) can be used to treat cardiovascular diseases such as hypertension, coronary heart disease, arrhythmias, and treatment of myocardial infarction after the acute event. Patients with compensated congestive heart failure may be treated with atenolol as a comedication (usually together with an ACE inhibitor, a diuretic and a digitalis-glycoside, if indicated). In patients with congestive heart failure, it reduces the need for and the consumption of oxygen of the heart muscle. It is very important to start with low doses, as atenolol reduces ... the muscular power of the heart, which is an undesired effect in congestive heart failure.
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Atenolol