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Asacol
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Asacol is a brand name for mesalamine, a medication given for the treatment of ulcerative colitis. Ulcerative colitis is an inflammation of the inner lining of the rectum and colon characterized by periods of remission. Symptoms alternate between flare-ups and remission, sometimes throughout a person’s whole life. When a person has a flare-up, the rectum or colon become inflamed, and people experience diarrhea, bleeding, abdominal cramps, and a feeling of urgently needing to go to the bathroom. Flare-ups can vary in how long they last and how severe they are. Asacol can ... be used to treat symptoms of Crohn’s disease, which is a digestive disorder similar to ulcerative colitis.
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Asacol is a prescription medicine that is used for treating ulcerative colitis in adults. It is thought to work by inhibiting the production of inflammatory chemicals in the lining of the colon. Asacol comes in the form of delayed-release tablets, which do not dissolve until they reach the very end of the small intestine. Side effects of Asacol can include a sore throat, belching, and stomach pain (or abdominal pain).
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Asacol has an excellent safety profile. Studies have shown that the number of people taking Asacol who withdrew as a result of side effects was low (less than 4%), similar to people taking a placebo(product containing no active ingredient). The side effects reported with Asacol are rare and usually mild. For more information, please ask your doctor.
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This study is designed to evaluate the safety and efficacy of Asacol® 2.4 g/day in generally healthy, adult patients who have had an attack of acute diverticulitis. The study will evaluate the safety and efficacy of a 12 week treatment with Asacol® followed a 9 month non-treatment observation period in approximately 180 patients with acute diverticulitis.
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Asacol contains aspirin. Aspirin has been associated with a serious illness called Reye syndrome. This disease causes numerous effects on human organs, especially the brain and liver. It is linked to the consumption of aspirin by children with viral disease such as chicken pox. Do not give Asacol to children or teenagers during or after chickenpox flu, or other viral infections without first consulting with your doctor.
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Of the 349 patients who received Asacol 2.4 g/day, 63 had isolated proctitis, 205 had left-sided disease (proctosigmoiditis and left-sided colitis) and 81 had pancolitis. Patients were prohibited from taking rectal therapies and were only treated with Asacol. The results showed that patients with isolated proctitis who took Asacol, dosed at 2.4 g/day for six weeks, experienced significant improvement as early as three weeks, and sustained improvement at six weeks, of UC symptoms. At six weeks 83% of patients had improvement in rectal bleeding, 75% had mucosal healing and 57% had reduced stool frequency.
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Asacol