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Asacol: Patients
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Asacol is a medication used in the treatment of mild to moderately active ulcerative colitis and the maintenance of remission of ulcerative colitis. Ulcerative colitis is a severe inflammatory disease affecting the colon and rectum. Patients with this disorder experience symptoms like bloody diarrhea, anorexia, abdominal pain, fever, and weight loss.
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Asacol 800, at 4.8 g/day, demonstrated an overall incidence of adverse events comparable to Asacol dosed at 2.4 g/day. Reported adverse events were generally mild and transient, and seldom resulted in discontinuation of treatment. Most commonly reported adverse events for Asacol 800 were nausea (6.1%), headache (5.4%), vomiting (4.1%) and flatulence (4.1%), while those for Asacol were headache (5.8%), abdominal pain (4.5%) and ulcerative colitis (3.9%). Patients should be made aware that ulcerative colitis rarely remits completely. Abrupt discontinuation of mesalamine therapy is not recommended and may result in relapse. Caution should be exercised in patients with hepatic dysfunction or history of renal disease.
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Clinical studies of Asacol did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. In general, the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy in elderly patients should be considered when prescribing Asacol. This drug is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken when prescribing this drug therapy. it is recommended that all patients have an evaluation of renal function prior to initiation of Asacol therapy and periodically while Asacol therapy continues.
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Asacol tablets have been evaluated in 3685 inflammatory bowel disease patients (most patients with ulcerative colitis) in controlled and open-label studies. Adverse events seen in clinical trials with Asacol tablets have generally been mild and reversible. Adverse events presented in the following sections may occur regardless of length of therapy and similar events have been reported in short- and long-term studies and in the post-marketing setting.
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The dosage of Generic for Asacol prescribed to each patient will vary. Always follow your physicians instructions and/or the directions on the prescription drug label. The following dosage information includes some common doses of Generic for Asacol. If your dose is different, do not follow any of the dosages described below unless your physician has approved.
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Asacol tablets are prescribed for patients with inflammatory bowel diseases such as mild to moderately active ulcerative colitis and for the maintenance of remission of ulcerative colitis. It works inside the bowel by helping to reduce the inflammation and other symptoms of the disease. Asacol may ... be prescribed to treat mild or moderate Crohn's disease and help prevent it from occurring again.
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