LYCOS RETRIEVER 
Antibiotics: Treatment
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Antibiotics are frequently used as a primary treatment approach in IBD, even though no specific infectious agent has been identified as the cause of these illnesses. However, researchers believe that antibiotics can help control symptoms of IBD by reducing intestinal bacteria and by directly suppressing the intestine's immune system.
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Healthy children greater than 2 years of age with uncomplicated, nonsevere AOM may be better off observed without antibiotics for 48-72 hours. Treatment for pain with pain relievers is appropriate. If severe symptoms (moderate to severe pain or fever above 102.2 degrees) develop or the child is not better in 48-72 hours, antibiotics can be prescribed at the time.
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Many antibiotics operate by inhibiting the synthesis of various intracellular bacterial molecules, including DNA, RNA, ribosomes, and proteins. The synthetic sulfonamides are among the antibiotics that indirectly interfere with nucleic acid synthesis. Nucleic-acid synthesis can ... be stopped by antibiotics that inhibit the enzymes that assemble these polymers—for example, DNA polymerase or RNA polymerase. Examples of such antibiotics are actinomycin, rifamicin, and rifampicin, the last two being particularly valuable in the treatment of tuberculosis. The quinolone antibiotics inhibit synthesis of an enzyme responsible for the coiling and uncoiling of the chromosome, a process necessary for DNA replication and for transcription to messenger RNA. Some antibacterials affect the assembly of messenger RNA, thus causing its genetic message to be garbled.
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Symptoms can begin during actual treatment or even up to four weeks after the course of antibiotics is over. However, clinical studies show that taking the probiotic Florastor, a yeast-based dietary supplement, along with the antibiotic, can control AAD by increasing the number of protective (good) micro-organisms in the intestinal tract. This yeast cannot be killed by the antibiotic.
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"We are encouraged by the research demonstrating the improved activity of oritavancin when compared with other glycopeptide antibiotics. By combining oritavancin with a common wetting agent, it is evident that the ability of the treatment to inhibit bacteria growth, demonstrated through previous research, may be underestimated based on these recent studies," said Thomas Parr, Ph.D., Chief Scientific Officer, Targanta Therapeutics. "These data further support oritavancin as a potential treatment for serious bacterial infections, and Targanta will continue to explore this potential through ongoing clinical research."
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A widespread myth holds that you shouldn't drink alcohol while taking antibiotics, but in fact, drinking doesn't lessen the effects of the drugs. However, alcohol can lower your general energy and delay your recovery so it is best to minimize drinking until you've finished the prescribed course of antibiotic treatment. (Beyond that, chronic liver damage from excessive alcohol consumption can affect the metabolism and toxicity of antibiotics.)
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