LYCOS RETRIEVER 
Angioedema: Swellings
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Angioedema is a less common reaction that has been associated with all ACE inhibitors. Most ACE inhibitor-induced angioedema involves the tongue, pharynx, or perioral tissues. No diagnostic test exists at present; the diagnosis is made on the classical history and ingestion of the ACE inhibitor. Visceral angioedema with ACE inhibitors is rare, but has been reported, and needs to be considered in the context of recurrent abdominal pain where no other cause has been identified.7
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Angioedema is a noninflammatory disease characterized by episodes of increased capillary permeability with extravasation of intravascular fluid and subsequent edema of the cutis or mucosa of the upper airways or gastrointestinal tract. It is characterized by one or recurrent attacks of edema of the face, upper airways, genitals, and limbs [1]. Edema of the mucous membranes of the mouth, throat, and nose may result in acute respiratory distress, airway obstruction, and asphyxia [1, 2]. Gastrointestinal involvement sometimes mimics an acute abdomen or rarely causes potentially life-threatening hypovolemic shock [1, 3].
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Angioedema is edema of the deep dermis and subcutaneous tissues. It is caused by exposure to drug, venom, dietary, or extracted allergens. The main symptom is diffuse, painful swelling, sometimes marked. Diagnosis is by examination. Treatment is elimination or avoidance of the allergen and H1 blockers.
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Angioedema is a rare genetic disorder that results in localized swelling and inflammation in the lips, mouth, throat, eyelids, genitals, hands and feet. The swelling varies from mild to severe; in the most severe cases, eyelids can swell shut, lips swell to resemble hot dogs and the tongue can become so large that speaking is difficult. When swelling occurs in the mouth or throat, the airway can become constricted, making breathing difficult. Angioedema that does not affect breathing usually goes away in a few days.
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Angioedema-associated eosinophilia (Gleich's syndrome) is a rare form that is ... associated with severe swelling of the face, lips, mouth, tongue, and extremities. Symptoms typically are intermittent, with severe exacerbations that usually respond to systemic corticosteroid treatment. Molecular mechanisms of this syndrome are unclear, but IV immunoglobulin (IVIG) has also been reported as a potential therapy for acute exacerbations.20
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Angioedema is a common condition that involves swelling beneath the surface of the skin with or without redness. Angioedema can occur around the eyelids and lips, or on the face, hands, feet, and genitalia. Since this condition can cause swelling of the airways, it is important that you seek medical care if you think you have angioedema.
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