LYCOS RETRIEVER
Anemia
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Anemia is a condition that should not be left untreated. If it is allowed to progress for a long period of time, anemia can become quite dangerous to your health. Anemia can result in the development of an irregular or rapid heartbeat (tachycardia) or an enlarged heart muscle (left ventricular hypertrophy). These conditions can increase your risk for heart disease or stroke. Anemia can ... leave you feeling terribly exhausted, making it difficult to enjoy work, school, or social events.
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Anemia has always been a problem for people with HIV and AIDS. The rate of serious anemia has dropped considerably since people started using ART. However, almost half of people with HIV still have mild or moderate anemia.
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Anemia can have a direct effect on prognosis and survival, and so, it may be very important to keep the hemoglobin at a higher level to decrease the effects of hypoxia, especially during treatment. There is a direct correlation between the hemoglobin level and the median P02 at the primary tumor site. There has ... been a well-known effect of tissue hypoxia in radiation therapy and anemia relating to the efficacy of radiation therapy. This has been well-evaluated in head and neck cancers, and it has been shown that tissue hypoxia has a negative impact on local control and survival in cervical cancer as well.The radiation therapy damages DNA through its production of hydroxyl radicals. Thus, under hypoxic conditions, there is a smaller amount of oxygen available to produce DNA damage from free radicals, and so, radiation therapy may be less effective.
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Anemia may have adverse effects on the heart and increase the severity of cardiac conditions, including reducing survival rates from heart failure and heart attacks. Elderly patients who are anemic for more than 2 days before heart surgery may have a greater risk for complications and death.
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Anemia may begin to develop in the early stages of kidney disease, when you still have 20 percent to 50 percent of your normal kidney function. This partial loss of kidney function is often called chronic renal insufficiency. Anemia tends to worsen as kidney disease progresses. End-stage kidney failure, the point at which dialysis or kidney transplantation becomes necessary, doesn't occur until you have only about 10 percent of your kidney function remaining. Nearly everyone with end-stage kidney failure has anemia.
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Anemia is actually a sign of a disease process rather than a disease itself. It is usually classified as either chronic or acute. Chronic anemia happens over a long period of time. Acute anemia happens quickly. Determining whether anemia has been going on a long time or whether it is something new helps doctors to find its cause. This ... helps predict how severe the symptoms may be.
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