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Advair Diskus
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Advair Diskus is a combination of two well-known and accepted products in one asthma inhaler. It is the first combination product for asthma to be offered in the United States that fights inflammation and airway constriction (bronchoconstriction). One of the constituent drugs in Advair Diskus, salmeterol (Serevent) a long-acting beta agonist, fights bronchoconstriction -- muscle tension around the bronchial tubes. The second medication is fluticasone (Flovent), a corticosteroid that helps reduce lung inflammation, irritation and swelling.
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"The approval of Advair Diskus 250/50 for this condition is important news for patients and physicians," said William Bailey, MD, professor of medicine and director of the Lung Health Center at the University of Alabama- Birmingham. "There is growing recognition that COPD is a complex disease with multiple components. Advair offers a new approach, because it contains both an anti-inflammatory and a bronchodilator that work together to improve lung function."
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Do not use Advair Diskus more often than your doctor has prescribed. Excessive use can cause heart irregularities. Use Advair Diskus with caution if you have any kind of heart disorder or high blood pressure. Alert your doctor immediately if you develop chest pain, heart palpitations, nervousness, or tremor.
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Advair Diskus, an oral inhaler containing a combination of fluticasone and salmeterol, is indicated for the twice-daily, long-term treatment of asthma in patients 12 years of age and older. Fluticasone, a steroid, and salmeterol, a long-acting beta-agonist, work to reduce swelling in the airways and relax and open air passages in the lungs. Advair controls asthma but does not cure the disorder. The U.S. Food and Drug Administration (FDA) approved Advair in 2000. The inhaler is made by GlaxoSmithKline.
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Advair Diskus contains a combination of salmeterol, a bronchodilator of the beta-2 agonist type, and fluticasone propionate, an anti-inflammatory corticosteroid. Beta-2 agonists are medications that attach to beta-2 receptors on the smooth muscle cells that surround the airways, causing the muscle cells to relax and open the airways. Fluticasone propionate is a synthetic (man-made) corticosteroid of the glucocorticoid family which is related to the natural hormone, cortisol or hydrocortisone, produced by the adrenal glands. Glucocorticoid steroids have potent anti-inflammatory actions. In asthmatic patients, the suppression of inflammation within the airways reduces the swelling caused by inflammation that narrows the airways. At the same time, mucus is reduced.
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Advair Diskus was first approved by the FDA in 2000. The medication contains two drugs: fluticasone and salmeterol, which in combination with one another help to reduce swelling in the airways and open up air passages in the lungs. Salmeterol is part of a class of drugs known as long-acting beta-agonists (LABA). LABAs were originally developed to help relax the muscles in the lungs... they have recently been linked with increasing the severity of asthma attacks.
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Advair Diskus