LYCOS RETRIEVER 
Addiction: Cocaine
built 606 days ago
It is estimated that approximately 15 percent of the world's adults have serious substance abuse problems (not including nicotine addiction), and that this percentage has remained fairly constant over the past twenty-five years. Of these substance abusers, about two-thirds abuse alcohol and one-third abuse other substances, mainly marijuana, amphetamines, cocaine, and heroin. Approximately2.5 percent of the population abuse marijuana, 0.5 percent abuse stimulants, 0.3 percent abuse cocaine or opioids (such as heroin), and up to 0.8 percent abuse other substances (e.g., inhalants, depressants, hallucinogens). Sites of drug production and manufacturing, and distribution routes, tend to identify regions at high risk for abuse.
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This trial is the third in a series of human trials conducted in Mexico, which successfully tested the safety and efficacy of vigabatrin to treat cocaine and/or methamphetamine addiction. These trials followed more than 15 years of animal studies conducted by Dr. Stephen Dewey at Brookhaven National Laboratory. All three human trials were conducted under the direction of Dr. Jonathan Brodie, the Marvin Stern Professor of Psychiatry at the New York University (NYU) School of Medicine and Dr. Emilia Figueroa, Director of the Clinica Integral de Tratamiento Contra las Adicciones, S.A. de C.V. The first two trials were small open-label studies. The trial's protocol was approved by NYU's Institutional Review Board in May 2006 and the Federal Commission for Sanitary Risks Protection (Mexico) in September 2006 and is registered at www.clinicaltrials.gov with the identifier NCT00527683.
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The Association of Chief Police Officers warned [15 February] that the UK could suffer an epidemic of methamphetamine addiction within two years. A class-A drug, it triggers violence and could be "as big a problem as crack cocaine".
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