LYCOS RETRIEVER 
Acyclovir: Doses
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Ask your health care provider incase Acyclovir Capsules might work with other medicines that you take. Check with your health care provider before you start, halt, or change the dose of any medicine.
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High doses of Acyclovir have proved dangerous in people whose immune system is compromised because of HIV infection, bone marrow transplant, or kidney transplant. If your kidneys are not functioning properly, or you are taking drugs that may damage the kidneys such as Neomycin or Streptomycin, Acyclovir can make your condition worse or affect your central nervous system (brain and spinal cord).
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Acyclovir is poorly absorbed from the GI tract following oral administration. The oral bioavailability ranges from 10 to 20% and decreases with increased doses. The Cmax and AUC are dose dependent and show no proportionality. The Cmax for a 200 mg dose is 0.83 mcg/ml, 1.21 mcg/ml with a dose of 400 mg, and 1.61 mcg/ml with a 800 mg dose. Oral absorption is not affected by food consumption.[1]
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The dosage of Generic for Acyclovir prescribed to each patient will vary. Always follow your physicians instructions and/or the directions on the prescription drug label. The following dosage information includes some common doses of Generic for Acyclovir. If your dose is different, do not follow any of the dosages described below unless your physician has approved.
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When taken by people with kidney disorders excessive doses of Acyclovir have been known to cause psychological problems and kidney failure. If you suspect an overdose, call or visit your local emergency room or clinic.
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