LYCOS RETRIEVER 
1918: 1918 Virus
built 194 days ago
In commenting on the ability of the 1918 virus to rapidly kill as documented in the Canadian study, "Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Disease at the National Institutes of Health, stated in an interview with the Associated Press, "There aren't a lot of things that can induce that robust of an inflammatory response that quickly."
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Katze's team will seek to learn more about the nature of the 1918 flu by inserting key genes from the killer flu into a common flu strain. The flu virus has only eight genes, said Katze, so they hope to rapidly target which genes are most responsible for virulence. The monkeys will be euthanized weeks after being infected, the UW scientists said, to allow for tissue, cellular and genetic testing.
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Scientists regenerated the 1918 virus Jurassic-Park-like from a frozen corpse two years ago. Now scientists have discovered that the regenerated virus can kill monkeys much as it killed humans in 1918, by kicking the immune system into dangerous overdrive, which ultimately kills the infected host.
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The virus was reconstructed using lung tissue recovered from two soldiers and an Alaskan woman who died during the 1918 pandemic. The tissue from the soldier's lungs had been saved in an Army pathology warehouse, and the tissue from the Alaskan woman's lungs was preserved as she was buried in permafrost.
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Working with Taubenberger's team, the NIH and others, the mice were infected by Tumpey with the fully reconstructed 1918 virus in a high-security lab. After the mice died, genetic samples from the lungs were sent to Katze's lab for analysis.
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Scientists have shown that tiny changes to modern flu viruses could render them as deadly as the 1918 strain which killed millions. A US team added two genes from a sample of the 1918 virus to a modern strain known to have no effect on mice.
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1918 Virus