Bloodletting is a procedure that was performed to help alleviate the ills of mankind. For an operation with a 3,000-year history, bloodletting has attracted little attention in recent historic accounts of medicine. Bloodletting began with the Egyptians of the River Nile one thousand years B.C., and the tradition spread to the Greeks and Romans; its popularity continued throughout the Middle Ages. It reached its zenith during the beginning of the nineteenth century, but had virtually died as a therapeutic tool by the end of that century.