About:Blank Hijackers are the most problematic browser hijackers currently on the Net. Tactics include using random names and multiple dlls that can replace each other when deleted, making it extremely difficult to locate and permanently remove all about:blank hijacker components. These programs are constantly being upgraded to stay ahead of the spyware removal programs that detect and remove them. They are worse than viruses in that respect. If your web browser always opens about:blank as its home page (aka start page) [A]nd you can't permanently change it using 'Tools > Internet Options', then a browser hijacker is the most likely cause of your about:blank problem.