* Lynn Margulis’ symbiosis theory is a proven theory in biology. * The claim in Acquiring Genomes that symbiosis is the main mechanism for creating new species in evolution is an unjustified extrapolation from a number of well-documented cases to all domains of life. * The claim that the accumulation of mutations do not lead to anything useful is refuted by the facts of molecular and evolutionary genetics. * Margulis unambiguously rejects creationism, despite her criticism of the fundamental neo-Darwinistic mechanisms, and her alternative theory is a fully naturalistic evolutionary theory.