Belladonna is most frequently propagated by seed, sown in flats in early March. Because the seeds take 4-6 weeks to germinate, they should be started early. When the seedlings are an inch or so high they may be set out 18 inches apart. The seedlings should be well watered just after transplanting, and shaded for several days. First-year plants will grow only 1.5 feet high and will flower in September. At this time the leaves and tops may be collected, but the plants should not be entirely stripped.