The main component in Primal Defense™ is HSOs™, which have been used for over 22 years by thousands of health care practitioners. The non-mutated naturally occurring colonies of probiotics are from the original, pristine cultures found in unpolluted soil and plants, now cultivated in U.S. laboratories using proprietary methods. The HSOs™ are in a substrate (subsoil or underlying layer) of nutrient rich superfoods providing vitamins, minerals, trace elements, enzymes and proteins. The probiotics are then made dormant using the Microflora Delivery System™, which protects and delivers them directly to the GI tract where they multiply and flourish.